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Latest reaction assists in new discovery

Chemists found a simplistic way that helps an ordinary block to be converted into a totally different and important compound. ETH Zurich’s chemists have recently found a way to convert ordinary building blocks into much paramount compounds. This has increased the chances of synthesis in chemicals and also eases up the research for new components in pharmaceuticals.

With growth in each and every field, medicines are also being made quite efficiently and precisely. These days, excessive research is needed to be conducted on various chemical compounds in order to find the active chemical compound that may have the required effect on the human body. Hence, a much more pivotal and critical study is to be done for the development of even more successful drug in the near future.

The chemists at the Laboratory of Organic Chemistry in Zurich have advanced the method of converting compounds generally found in medicines and natural environment, into important compounds by a much simpler way. Since, the indole chemical compounds are not appropriate in the existing chemical libraries, the resulting compounds have a broader prospective for revealing biological reaction. This research by the ETH Zurich’s scientists has been published in ‘Science’.

The scientists claim that the method, Ciamician-Dennstedt, is derived from some old tricks by a doctoral student, named Julia Reisenbauer, in the 19th century. She claimed her inspiration behind this method was a particular chemical compound. She explained that the method can be applied in order to establish a single carbon compound to the world of aromatic ring compounds. However, there is always an exception in chemistry. Inserting a nitrogen atom was a bit challenging, so a brand-new approach was introduced and used, which the hypervalent iodine reagent, which helped the “naked” nitrogen atom enter the ring compound/system

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